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Caris Life SciencesCAI.OValuation Analysis

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Valuation Snapshot

Based on the blended 10-year P/E and P/B percentiles, the stock currently sits in the “Richly Valued” zone.

As of Oct 16, 2026, Caris Life Sciences (CAI.O) trades at a P/E of 82.00x, P/B of 14.60x, P/S of 8.73x, and a dividend yield of 0.00%.
Longitudinal percentile comparison: P/E sits at the 94th percentile over the trailing 10Y window (vs. 94th percentile over 3Y); P/B sits at the 63rd percentile over the trailing 10Y window (vs. 63rd percentile over 3Y); P/S sits at the 56th percentile over the trailing 10Y window (vs. 56th percentile over 3Y).
Cross-sectional valuation: its P/E ranks at the 86th percentile within its industry and the 92nd percentile across the broader market.
Shareholder return highlight: Total Shareholder Yield is 0.00%, ranking at the 43rd percentile over the trailing 20Y window.
The P/E and P/B percentiles diverge here, differing by 30.9 points — relying on either metric alone could be misleading. Its P/E percentile is roughly the same whether measured against the industry or the broader market. Shareholder returns here are driven almost entirely by cash dividends, with minimal contribution from buybacks. Caris Life Sciences operates in the Services sector. Data refreshes weekly and is for reference only, not investment advice.

Also listed as: NASDAQ: CAI · CAI

Want the full picture on whether Caris Life Sciences (CAI.O) is under- or over-valued? See the full 3Y / 5Y / 10Y / 20Y P/E, P/B, P/S, Dividend Yield & Total Shareholder Yield percentile matrix and the interactive ECharts trend chart on this page.

P/E PE (TTM) 82.00
MarketRich
IndustryRich
3YRich
5YRich
10YRich
20YRich
P/B PB (MRQ) 14.60
MarketRich
IndustryRich
3YFair
5YFair
10YFair
20YFair
P/S PS (TTM) 8.73
MarketRich
IndustryRich
3YFair
5YFair
10YFair
20YFair
Dividend Yield 0.00%
Market0
Industry0
3Y0
5Y0
10Y0
20Y0
Buyback + Div Yield 0.00%
MarketFair
IndustryFair
3YFair
5YFair
10YFair
20YFair

Historical P/E (Weekly)

MetricCurrentMarket PercentileIndustry Percentile 3Y Pctl5Y Pctl10Y Pctl20Y Pctl
P/E (TTM)82.00
91.8%
86.2%
93.8%
93.8%
93.8%
93.8%
P/B (MRQ)14.60
94.5%
90.8%
62.9%
62.9%
62.9%
62.9%
P/S (TTM)8.73
86.1%
86.5%
55.9%
55.9%
55.9%
55.9%
Dividend Yield0.00%000000
Buyback + Div Yield0.00%
46.0%
47.0%
42.9%
42.9%
42.9%
42.9%
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