ExelixisEXEL.OValuation Analysis
Based on the blended 10-year P/E and P/B percentiles, the stock currently sits in the “Fair Value Range” zone.
As of Oct 16, 2026, Exelixis (EXEL.O) trades at a P/E of 17.90x, P/B of 8.40x, P/S of 6.33x, and a dividend yield of 0.00%.
Longitudinal percentile comparison: P/E sits at the 34th percentile over the trailing 10Y window (vs. 50th percentile over 3Y); P/B sits at the 82nd percentile over the trailing 10Y window (vs. 100th percentile over 3Y); P/S sits at the 59th percentile over the trailing 10Y window (vs. 100th percentile over 3Y).
Cross-sectional valuation: its P/E ranks at the 34th percentile within its industry and the 46th percentile across the broader market.
Shareholder return highlight: Total Shareholder Yield is 6.61%, ranking at the 91st percentile over the trailing 20Y window.
Notably, P/E and P/B aren't telling quite the same story, 48.0 points apart — worth checking the full percentile matrix on this page for the complete picture. The P/E percentile sits lower within its industry than across the market as a whole — relatively cheaper next to direct peers. Shareholder returns here lean heavily on buybacks rather than cash dividends. Exelixis operates in the Manufacturing sector. Data refreshes weekly and is for reference only, not investment advice.
Also listed as: NASDAQ: EXEL · EXEL
Want the full picture on whether Exelixis (EXEL.O) is under- or over-valued? See the full 3Y / 5Y / 10Y / 20Y P/E, P/B, P/S, Dividend Yield & Total Shareholder Yield percentile matrix and the interactive ECharts trend chart on this page.
Historical Percentiles by Metric
| Metric | Current | Market Percentile | Industry Percentile | 3Y Pctl | 5Y Pctl | 10Y Pctl | 20Y Pctl |
|---|---|---|---|---|---|---|---|
| P/E (TTM) | 17.90 | ||||||
| P/B (MRQ) | 8.40 | ||||||
| P/S (TTM) | 6.33 | ||||||
| Dividend Yield | 0.00% | 0 | 0 | 0 | 0 | 0 | 0 |
| Buyback + Div Yield | 6.61% |