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RegeneronREGN.OValuation Analysis

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Valuation Snapshot

Based on the blended 10-year P/E and P/B percentiles, the stock currently sits in the “Fair Value Range” zone.

As of Oct 16, 2026, Regeneron (REGN.O) trades at a P/E of 18.80x, P/B of 2.57x, P/S of 5.24x, and a dividend yield of 0.36%.
Longitudinal percentile comparison: P/E sits at the 51st percentile over the trailing 10Y window (vs. 62nd percentile over 3Y); P/B sits at the 14th percentile over the trailing 10Y window (vs. 46th percentile over 3Y); P/S sits at the 28th percentile over the trailing 10Y window (vs. 38th percentile over 3Y).
Cross-sectional valuation: its P/E ranks at the 37th percentile within its industry and the 49th percentile across the broader market.
Shareholder return highlight: Total Shareholder Yield is 5.24%, ranking at the 92nd percentile over the trailing 20Y window.
Notably, P/E and P/B aren't telling quite the same story, 36.8 points apart — worth checking the full percentile matrix on this page for the complete picture. The P/E percentile sits lower within its industry than across the market as a whole — relatively cheaper next to direct peers. Of the 5.24% total shareholder yield, 0.36% is paid out as dividends and roughly 4.88% is implied to come from buybacks — both channels are meaningfully in play. Regeneron operates in the Manufacturing sector. Data refreshes weekly and is for reference only, not investment advice.

Also listed as: NASDAQ: REGN · REGN

Want the full picture on whether Regeneron (REGN.O) is under- or over-valued? See the full 3Y / 5Y / 10Y / 20Y P/E, P/B, P/S, Dividend Yield & Total Shareholder Yield percentile matrix and the interactive ECharts trend chart on this page.

P/E PE (TTM) 18.80
MarketFair
IndustryFair
3YFair
5YFair
10YFair
20YFair
P/B PB (MRQ) 2.57
MarketFair
IndustryFair
3YFair
5YCheap
10YCheap
20YCheap
P/S PS (TTM) 5.24
MarketRich
IndustryRich
3YFair
5YFair
10YCheap
20YCheap
Dividend Yield 0.36%
MarketFair
IndustryCheap
3YFair
5YCheap
10YCheap
20YCheap
Buyback + Div Yield 5.24%
MarketCheap
IndustryCheap
3YCheap
5YCheap
10YCheap
20YCheap

Historical P/E (Weekly)

MetricCurrentMarket PercentileIndustry Percentile 3Y Pctl5Y Pctl10Y Pctl20Y Pctl
P/E (TTM)18.80
49.2%
36.8%
61.8%
65.5%
50.8%
36.2%
P/B (MRQ)2.57
66.4%
54.7%
46.5%
28.0%
14.0%
8.0%
P/S (TTM)5.24
77.2%
73.2%
38.2%
40.2%
28.2%
20.6%
Dividend Yield0.36%
65.4%
77.1%
50.3%
70.1%
85.1%
92.5%
Buyback + Div Yield5.24%
80.2%
90.5%
77.7%
82.4%
83.1%
91.6%
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